We surmise that results obtained from the experiments described in this section cannot serve to understand the role of INaL in arrhythmogenesis.
step 1. Van Driessche W, Lindemann B: Attention dependence off currents using unmarried salt-selective skin pores during speechwriting services the frog body. Characteristics. 1979; 282 (5738): 519-520 PubMed Conceptual | Creator Complete Text message
It indicates this new strong conclusions put forward through this manuscript was maybe not warranted and i also you should never approve this new manuscript contained in this mode
Brand new people keeps made clear a number of the questions I elevated within the my past remark. Unfortuitously, all big issues haven’t been handled by this update. When i made in my personal past comment, We deem it unlikely that every men and women points are set simply because of the a few added paragraphs. Instead you may still find specific important issues with the fresh build and you will, really significantly, to the studies.
This means new strong findings submit by this manuscript is maybe not rationalized and i usually do not approve the newest manuscript within this form
The fresh new article authors has explained many of the inquiries I raised in my earlier in the day feedback. Sadly, all biggest trouble have not been managed by this improve. Once i stated in my personal prior opinion, I consider it unrealistic that all those individuals facts shall be solved simply because of the several extra sentences. As an alternative you may still find certain fundamental inquiries toward experimental framework and you can, very significantly, for the analysis.
- The very best concern is that in case We implemented the latest breakdown of the ways in the last adaptation it had been you can easily to help you decode, with almost finest precision, any random stimuli names I chose. Come across having samples of that it reanalysis. Whether or not we pretend your real stimulus searched on a later time or try consistently changing ranging from rule and you may quiet, the new decoding is close to prime. This is exactly indicative your decoding doesn’t have anything to complete to the actual stimulus read by the Sender it is opportunistically exploiting more enjoys regarding the data. The brand new handle studies the newest people did, reversing the newest stimuli brands, do not address this matter since it suffers from equivalent situation. Fundamentally, what the classifier is presumably having fun with it’s time who has enacted because recording started.
- The reason behind that is presumably that the people used non-independent data getting training and you may assessment. Of course, if I am aware correctly (select section 3), arbitrary testing half of data products of a keen EEG shade commonly independent studies. Recurring the analysis five times – new control investigation brand new article authors performed – is not a sufficient solution to target so it question. At random shopping for products regarding a time series that has had sluggish change (for instance the sluggish trend pastime one to allegedly reigns over these recordings less than these scenarios) often invariably include good temporal correlations. Get a hold of TemporalCorrelations.jpg set for 2D density histograms and you can a correlation matrix indicating it.
- Due to the fact modified actions part provides increased detail now, they is still confused about what studies were utilized. Old-fashioned classification study report just what studies has actually (typical articles throughout the research matrix) and you can just what observations (usual rows) were used. Anything might possibly be a feature however, typically this can be the some other EEG channels otherwise fMRI voxels etcetera. Observations are often time circumstances. Here I assume the new writers transformed the latest raw examples towards an effective additional place having fun with principal component data. This is simply not stated in the event the dimensionality try shorter with the eigenvalues. Regardless, I guess the content trials (collected in the 128 Hz) had been following put as observations together with EEG streams turned of the PCA were used because enjoys. The fresh stimuli brands was tasked as For the or From each try. Some 50% from products (and you may names) ended up being selected at random to own education, and also the other people was applied having testing. Is it best?